Filling Machines

• Aseptic Sterile Filling

  Optima Pharma offers an innovative machine portfolio for the filling of sterile liquids and powders. Intelligent process equipment reduces the system's process times and downtimes significantly. Minimizing product loss to one object per batch has already been made possible by using intelligent filling. Suitable for:

  • Prefilled syringes
  • Vials
  • Infusion Bottles
  • Cartridges

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• Blow - Fill - Seal BFS

  Packaging of liquids and semisolids in plastic containers. Rommelag’s bottelpack machines with German engineering and Swiss precision can manufacture canisters, bottles, tubes, ampoules, drop bottles, bellows containers, and portion packaging in a variety of forms and plastic blends, with filling volumes ranging from 0.04 to 10,000 ml, aseptically or conventionally – fully automatically.

  • Human intervention is excluded completely
  • The product is always secured in a sterile environment
  • Increased productivity

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• Tube fillers

  Automatic tube filling and closing machine for metal, plastic, polyfoil and laminate tubes with cassette infeed system. Designed and constructed according to the highest technological standards to guarantee the maximum productivity and quality. Designed according to G.M.P. standards and therefore suitable for sterile rooms and laminar flows. Bergami produces machines suitable not only for cosmetics but also for pharma applications in sterile rooms ensuring quality, productivity and dependability.

  • All types of tubes
  • Automatic feed
  • G.M.P. compliance

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• Isolators - RABS

  Isolators and RABS from METALL+PLASTIC can be used universally. Integration into all forms of pharmaceutical production systems is made possible thanks to our many years of experience in design, production, installation, qualification and validation as well as cycle development.

  • Sterile filling of liquids and powders
  • Loading and unloading freeze-dry systems
  • E-Beam tunnel used to decontaminate syringe tubs
  • Sterility testing isolators
  • Laboratory isolators
  • Transfer isolators
  • H2O2 transfer chambers / channels
  • Gastight doors

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• Freeze Dryers

  Optima provides freeze-drying solutions for all production sizes, from small batches for clinical trials to large production batches. Their modular design means that your processes are scalable and the systems can be optimally adapted to suit your production infrastructure.Our expertise comes from a combination of our in-depth knowledge of the latest lyophilization solutions and cutting edge engineering technology. Comprehensive turnkey project management massively reduces the complexity of project control, from interdisciplinary consulting to uniform interfaces and documentation to the centralized SCADA system for the entire plant. Fields of application:

  • Biotech
  • High potent active ingredients
  • nRNA vaccines
  • Peptides and ologonucleotides
  • Viral vectors
  • Blood plasma
  • Freeze-dried beads
  • Diagnostics

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